The disease impacts so many people in so many different ways, including the severity of it's impact. It ranges from people who have very infrequent Migraine attacks, and never need anything more than a nap or a simple over-the-counter treatment to people who live with Chronic Migraine. Based on current U.S. census figures, nearly 41 million Americans have Migraine disease.


People with Chronic Migraine have Migraine attacks or headaches 15 or more days a month, at least eight of which must be Migraine days. In other words, they have a Migraine or headache more often than not. The current estimate is that approximately 3.2 million Americans are living with Chronic Migraine.


In many minds, Migraine is a public health crisis. At this time, there are NO medications available for Migraine prevention that were originally developed for that purpose. One of the biggest reasons for this is a lack of funding for seminal Migraine research that is necessary for researchers to have a better understanding of the pathophysiology and epidemiology of Migraine disease. Despite lobbying efforts, the National Institutes of Health (NIH) continues to NOT attempt to balance research funding with disease burden.

One of the most difficult situations a Migraine patient can experience is having chronic Migraine and medication overuse at the same time. To add to these issues, there's another one — the best treatment strategy for those of us with simultaneous chronic Migraine and medications overuse is uncertain. Doctors have been using two different treatment strategies for these patients, but there's insufficient evidence as to which of the two is better.


The good news is that the Patient Centered Outcomes Research Institute (PCORI) is funding a five-year study to determine which treatment strategy works better for patients.


The study is the Medication Overuse Treatment Strategy (MOTS) Trial. For more information, please visit the MOTS Trial web site.

Living with Migraine disease presents many challenges. It's vital to have a good, knowledgeable doctor to work with as treatment partners. Equally important is that both patient and doctor combine their aptitude for learning about Migraine with a positive attitude toward exploring treatment options. This combination is Migratude. Please take a moment to read Sunday Thoughts on Living With Migraine - Doctors and Migratude.

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last updated July23, 2017


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